Milan is the capital of the Lombardy region, and the most populous metropolitan area and the second most populous comune in Italy. Milan is an Alpha leading global city, with strengths in the arts, commerce, design, education, entertainment, fashion, finance, healthcare, media, services, research, and tourism. The city is a major world fashion and design capital, well known for several international events and fairs, including Milan Fashion Week and the Milan Furniture Fair. The city hosts numerous cultural institutions, academies and universities, with 11% of the national total enrolled students. Milan's museums, theatres and landmarks (including the Milan Cathedral, Sforza Castle and Leonardo da Vinci paintings such as The Last Supper, a UNESCO World Heritage Site) attract millions of visitors annually.